Introducing CBN: The new hemp cannabinoid taking the hemp industry by storm
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When it comes to the hemp plant, THC delta-9 and CBD (cannabidiol) are its two most well known compounds. These cannabinoids have gotten so much attention that you might be surprised to find out there are actually over 100 more cannabinoid compounds that come from this well-known plant. Each one having its own unique properties.
If you’re curious about what else this plant could potentially offer, you’re not alone.
Researchers are starting to focus more of their attention on the lesser-known siblings of THC and CBD, and CBN is one of these cannabinoids that scientists are trying to understand better.
What is CBN?
CBN is short for cannabinol, and it’s a non-psychoactive, chemical compound derived from hemp plants. As a minor cannabinoid, it can be found in trace amounts in most plants. What makes it so unique is that it doesn’t start appearing in high concentrations until tetrahydrocannabinol (THC) starts to degrade.
As THC degrades, CBNa, the acidic form of CBN, is produced from THCa, the acidic form of THC. Outside of this, there are other ways to produce cannabinol including heat, UV lighting, and oxygen. These techniques simply help speed up the natural degradation process that the THC cannabinoid goes through.
CBN’s unique life cycle and rarity mean it’s not realistic to extract it directly from hemp plants like other types of cannabinoids. Instead, it’s extracted using methods like chromatography that help isolate different compounds, even ones with lower concentrations.
What about CBN for sleep?
Cannabinol (CBN) isn’t that well-known, but those who do know about it, understand it can be used as a potential natural sleep aid. Unfortunately, the use of CBN for sleep doesn’t have much research to back it up, but there has been some research you may find of interest. One 1995 study found that cannabinol significantly prolonged the length of time that mice slept.
Here is some research you may find interesting, a 2019 study found that cannabinol works as an even more potent sedative taken in combination with other compounds. That may be because cannabinoids have the ability to work together to enhance the effects in a phenomenon is known as the entourage effect.
How to use it
With CBN research still in its infancy and the difficulty of producing large quantities, finding this cannabinoid can be challenging. Luckily, if you’re interested in trying it you’ve come to the right place! We have CBN products that are already balanced with the perfect amount of CBN + CBD so you can get the maximum use of your cannabinoids.
Infusionz carries three CBN products to provide you with an option that best fits your needs.
- CBN Oil Tincture: 150mg CBN and 450mg CBD
- CBN Fruit Snacks: 150mg CBN and 450mg NANO Water Soluble CBD
- CBN Capsules: 100mg CBN and 400mg NANO Water Soluble CBD
Cannabinol Studies and Research
The number of studies regarding CBN is not as plentiful as other cannabinoids like CBD or THC, but things are starting to pick up. The research is promising, which leaves us feeling optimistic about future studies so we can develop an even better understanding of this compound.
Keep reading to see what researchers have learned so far.
Comparative Study: Here is a study done by researchers at the Department of Neurology, University of Washington, Seattle, WA 98195, USA.
- Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival
- Patrick Weydt 1, Soyon Hong, Anke Witting, Thomas Möller, Nephi Stella, Michel Kliot
- “We therefore tested whether cannabinol (CBN), a non-psychotropic cannabinoid, influences disease progression and survival in the SOD1 (G93A) mouse model of ALS. CBN was delivered via subcutaneously implanted osmotic mini-pumps (5 mg/kg/day) over a period of up to 12 weeks.”
Structure−Activity Study: This study was done by several researchers from several European universities, where they looked at the antibacterial properties of five different cannabinoids, CBN included.
- Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
- Giovanni Appendino, Simon Gibbons, Anna Giana, Alberto Pagani, Gianpaolo Grassi, Michael Stavri, Eileen Smith, and M. Mukhlesur Rahman
- “…been known to contain antibacterial cannabinoids, whose potential to address antibiotic resistance has not yet been investigated. All five major cannabinoids (cannabidiol (1b), cannabichromene (2), cannabigerol (3b), Δ9-tetrahydrocannabinol (4b), and cannabinol (5)) showed potent activity against a variety of…”
Comparative Study: Scientists from School of Pharmacy, University of Reading, Whiteknights, Reading, Berkshire, RG6 6AJ, UK, studied the effects that cannabigerol, cannabidiol, and cannabinol had on the appetites of rats.
- Cannabinol and cannabidiol exert opposing effects on rat feeding patterns
- Jonathan A Farrimond 1, Benjamin J Whalley, Claire M Williams
- “However, possible non-∆(9)-tetrahydrocannabinol phytocannabinoid-induced feeding effects have yet to be fully investigated. Therefore, we have assessed the effects of the individual phytocannabinoids, cannabigerol, cannabidiol and cannabinol, upon feeding behaviors.”
Review: Here researchers did a review on several cannabinoids, including cannabinol, to see how they interact with the body when inflammation is present.
- Cannabinoids, inflammation, and fibrosis
- Robert B. Zurier Sumner H. Burstein
- “A concise survey of the anti‐inflammatory actions of the phytocannabinoids ∆9‐tetrahydrocannabinol (THC), cannabidiol, cannabichromene, and cannabinol is presented.”