Studies, Research, & Relevant Articles on Cannabinoids

Topical / Transdermal

Study – The effects transdermal cannabidiol (CBD) has on rats with arthritis –

Researchers from the University of Kentucky applied a Transdermal CBD Gel directly to the arthritic knee of the rat, and then took note on its effects on inflammation and pain.

Conclusion – Significant reduction in swelling and what appeared to be relief from pain by how the rats held their affected joints led the researchers to conclude that CBD topicals “therapeutic potential for relief of arthritis pain-related behaviours and inflammation without evident side-effects”.

Study – The effects of cannabidiol (CBD) has on mice in an experimental model of autoimmune encephalomyelitis (EAE). **Note – this model is the most commonly used model for multiple sclerosis (MS). –

A study published in DARU Journal of Pharmaceutical Sciences reviewed how a purified CBD used as a topical treatment in an experimental model of EAE could affect disease progression and recovery of hind leg paralysis.

Conclusion – The results showed great promise that daily use could exert neuroprotective agencies against the autoimmune disease and a drop in the clinical disease score with the recovery of hind leg paralysis. “All these data suggest an interesting new profile of CBD that could lead to its introduction in the clinical management of MS and its associated symptoms at least in association with current conventional therapy.” the researchers concluded.

*The FDA has not evaluated these statements, and this article is not intended to diagnose, treat, or cure any diseases or ailments. Always check with your doctor before starting this or any other supplemental routine.