What Is CBD?
FDA Disclaimer: "Although CBD has been found to be safe for humans and has no to minimal side effects for most people, we recommend you do research before adding CBD to your routine.
If you are taking medications - consult your doctor! Until we have more research on how CBD interacts w/ medications, it’s important to work closely with your regular doctor.
CBD is being used by many people to help with a wide range of conditions, but it’s important to remember that these different uses may be supported with different levels of research and evidence on CBD’s benefits."
You’ve seen the headlines and heard the buzz. What is CBD?
CBD, or Cannabidiol, is one of hundreds of cannabinoids that are found in marijuana and industrial hemp plants. Unlike THC, it is non-psychoactive cannabinoid, which means it doesn’t get you high. Because of this, CBD will not adversely affect behavior, sensory awareness, perception, reaction time, or consciousness. After THC, it is currently the most studied cannabinoid, and is the most naturally-occurring cannabinoid found in cannabis. Although CBD can’t get you high, it has many of the same medicinal properties of THC.
Okay let’s back up. What is a cannabinoid?
A cannabinoid is part of a group of diverse chemical compounds that can act on cannabinoid receptors in the body’s cells, which can alter neurotransmitter release in the brain. There are three different groups of cannabinoids -
which are produced naturally in the body
which are found in cannabis (marijuana and hemp plants) and some other plants
which are manufactured artificially
CBD falls into the phytocannabinoid group. The Phytocannabinoids have been shown to affect inflammation, pain sensation, appetite, metabolism, thermoregulation, vision, mood, and memory. To be considered a phytocannabinoid, the plant-derived product must be capable of directly interacting with cannabinoid receptors, share similarities with other cannabinoids that interact with the endocannabinoid system, or both.
What’s the difference between Hemp CBD and Marijuana CBD?
CBD can be derived from the Hemp plant and the Marijuana plant, which are both part of the cannabis plant family. Unlike marijuana plants, hemp contains less than 0.3% of THC, and the two cannabis plants have very different uses and production. Most CBD products use hemp CBD because of its ability to be sold in all 50 states of the U.S. under specific conditions.
CBD - Front and Center
With CBD’s incredible safety profile and its ability to interact with the human endocannabinoid system and multiple organ systems, CBD has been put into the spotlight with its potential uses and benefits. The scientific and medical communities are currently conducting trials and studies with CBD to find its potential uses and benefits for many conditions including epilepsy, convulsions, cancer, multiple sclerosis, spasms, bipolar disorder, anxiety disorders, schizophrenia, nausea, and inflammation.
Preclinical trials and studies have shown extreme promise in:
- Anti-Tumoral Agent
As a chemical substance, CBD has strong antioxidant properties, and has been shown to inhibit the growth of a strain of staphylococcus resistant to antibiotics, MRSA bacterium, which causes multiple difficult-to-treat infections. Some people say they’ve experienced stress reduction, inflammation and pain reduction, while others say CBD promotes overall health and wellness.
At the end of this article we have provided links to relevant studies and research that show promise for the conditions above. Take me there now!
Unfortunately, research, studies, trials, and funding on cannabis research have mostly been limited to government overreach and federal laws. With CBD’s gaining popularity, more and more research is being done to explore this cannabinoids potential.
Although more trials and research need to be conducted to fully know the benefits of CBD, even the FDA has started to come around to the potential.
What forms does CBD come in?
The most potent type of CBD product is pure CBD oil. After being successfully extracted from the cannabis plant, the CBD oil is tested for quality and then packaged. No other additives go into the oil. This is an ideal method of intake when someone is looking for a higher concentration per serving.
This is a great way to get CBD into a daily routine, with the CBD capsules being as easy to take as a multivitamin. With servings typically ranging at 25mg and up, this method is good for people wanting a moderately high concentration per serving.
CBD Tinctures / Liquids
CBD tinctures and liquids are made by diluting the pure CBD oil into a natural oil base or an alcohol. This is perfect for someone looking for a smaller serving of CBD, with ranges of 1 to 20mg per serving. For most, this is serving size is perfect for what they’re wanting.
These salves and balms are not ingested, but are rubbed directly onto the skin. These soothing CBD topicals are used to hit specific trouble areas of the skin, muscles, and joints.
This is definitely an extremely fun way someone can get their CBD. Manufactures have started to create hard candies, gummies, licorice, and other tasty treats infused with CBD. These CBD edibles typically come in 5 - 20mg options.
As more and more research is conducted, the potential benefits of CBD seem extremely promising to those suffering from hard to treat conditions and those wanting a safer alternative to prescription medications without the harsh side effects. Continuing reading below for definitions and studies!
There can be a lot of confusing terms in regards to cannabis and Cannabidiol. Below are some definitions to help!
Cannabis – This is a kind of flowering plant, that includes the hemp and marijuana plant. Most commonly associated with marijuana and its use as a recreational drug, the hemp plant of the species has stepped into the spotlight in recent years.
Hemp –This is a high-growing variety of cannabis, that typically has less than 1% THC in the entire plant. Hemp is very popular for refining into products such as cloth, paper, fuel, hemp oil, rope, and more.
Cannabinoids – Two of the most well known Cannabinoids are THC and CBD, but are actually a very diverse chemical family that can come from certain plants, your own body, as well as be created synthetically.
CBD – This cannabinoid is found in the cannabis plant, and is legal and safe to consume.
THC – THC is a psychoactive cannabinoid, meaning when taken it gets a person 'high'. The production and usage are strictly regulated, with it being illegal in most U.S. states.
Psychoactive – This is a chemical substance that can enter the brain from the bloodstream, and directly affects the central nervous system.
Studies / Reviews / Clinical Trials
Safety & Side Effect - Review - http://online.liebertpub.com/doi/full/10.1089/can.2016.0034
Safety & Side Effects - Review - https://www.ncbi.nlm.nih.gov/pubmed/22129319
Epilepsy - Open-Label Interventional Trial - https://www.ncbi.nlm.nih.gov/pubmed/26724101
Dravey Syndrome - Double-Blind Trial - http://www.nejm.org/doi/full/10.1056/NEJMoa1611618?query=featured_home&
Anxiety - Preliminary Study - https://www.ncbi.nlm.nih.gov/pubmed/21307846
Parkinson’s - Exploratory Double-Blind Trial - https://www.ncbi.nlm.nih.gov/pubmed/25237116
Parkinson’s - Open Pilot Study - https://www.ncbi.nlm.nih.gov/pubmed/3793381
Schizophrenia - Double-Blind Clinical Trial - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316151/
Dystonia - Pilot Study - https://www.ncbi.nlm.nih.gov/pubmed/3793381
Graft vs Host Disease - Phase II Study - http://www.sciencedirect.com/science/article/pii/S1083879115003754
Nicotine Addiction - Pilot Double-Blind Study - https://www.ncbi.nlm.nih.gov/pubmed/23685330
THC Impairment & Withdrawal - Double Blind Experiment - https://www.ncbi.nlm.nih.gov/pubmed/6285406
THC Impairment & Withdrawal - Proof of Concept Study - https://www.ncbi.nlm.nih.gov/pubmed/26925704
Treatment Resistant Conditions - Review - https://www.ncbi.nlm.nih.gov/pubmed/18404144